The DAO level measured by the histamine test can be influenced by the following factors:
“DAO preparations”, such as DAOsin
excessive alcohol and nicotine consumption
short-term medication (N-acetylcysteine, ambroxol, aminophylline, amitriptyline, chloroquine, clavulanic acid, isoniazid, metamizole, metoclopramide, propafenone, verapamil, etc.).
Some of these drugs do not specifically affect DAO, but only histamine release. In general, the influence of drugs on DAO is not 100% guaranteed. Permanent medication is not meant by this because of essential regular intake, as it has a “permanent” influence.
Since the main site of formation of diamine oxidase is the intestine, all diseases or influences on the gastrointestinal tract also have an effect on the formation of the enzyme.
Certain foods are suspected to influence DAO levels – including cocoa, green and black tea and energy drinks.
The supply of vitamin B6, zinc and vitamin C also has an influence on the DAO level, as DAO cannot be sufficiently formed in the event of a deficiency.