Coronavirus testen

Knowledge means security.

kiweno helps people to take control of your health. In the past, but also especially now in health crises.

The disease COVID-19 left the world standing still for a few weeks. For a normal everyday life to become reality, clarity about the health condition of each individual must be created. An important issue here is testing to create knowledge and thus, to a certain extent, security. On the one hand, testing is important for making personal decisions, but on the other hand, it is also important for determining social and societal conditions. This topic will continue to occupy us for several months.

Overview TESTING

COVID-19 can be roughly differentiated between acute and antibody tests.

An acute test is used to detect an acute infection with the SARS-CoV-2 virus, for which so-called PCR tests (PCR = polymerase chain reaction) are suitable. A PCR test involves the direct detection of viruses with a throat swab. Evaluation in a specialist laboratory is necessary for this.

So-called antibody tests are used to detect an infection that has already subsided and has been overcome. These tests are suboptimal in the acute phase, but very important for the later course of the disease. IgG antibody tests are particularly interesting here. IgG antibodies are formed in the course of an infection and are considered the “memory” of the immune system. They can be detected in the blood for several months.

When does which coronavirus test make sense?

  1. Each test has its justification in different phases. If COVID-19 is suspected, an acute test by means of a PCR test (throat swab) is useful to determine an acute infection. At the beginning of an infection, the greatest viral load is in the respiratory tract and throat. After a few days, however, the viral load there becomes lower and lower and the disease can then no longer be reliably detected.
  2. During the infection, the immune system reacts quickly by producing antibodies – IgM antibodies in the first few days and IgG antibodies later. IgM antibodies therefore indicate an acute infection, while IgG antibodies form the memory of the immune system and indicate that the infection has already been overcome. They are only formed a little later (after about 14 days they can be reliably measured) and then remain in the body for a very long time (several months) to ward off further infections.
  • Antibody tests for IgG antibodies are evaluated in the laboratory using the so-called ELISA method. The ELISA method is one of the safest and most accurate methods for evaluating antibodies.
  • In the meantime, however, there are already very accurate rapid tests for IgG antibodies. The accuracy varies from manufacturer to manufacturer, but is in most cases already very good at over 98%.

FAQ

The test system of the kiweno vitamin d rapid test consists of an immunological rapid test, which detects vitamin D (25(OH)-vitamin D) using specific antibodies, and a smartphone app, which quantitatively evaluates the result of the rapid test based on the colour intensity of the control and test band. The result is displayed and stored on the smartphone in use. The system requirements and supported devices can be found at kiweno.com/vitd-schnelltest

Your samples are evaluated with standardized test procedures. A distinction is made between ELISA and ICP-MS procedures.

What is the ICP-MS procedure?

The ICP-MS method (inductively coupled plasma mass spectrometry) is a mass spectrometry method in which the mass of atoms and molecules can be measured. This very precise method allows even the smallest concentrations of elements such as zinc, magnesium and selenium to be measured. These are interpreted as your result.

What is the ELISA test method?

The standardised ELISA (enzyme-linked immunosorbent assay) test procedure detects certain molecules (such as proteins or antibodies) in body fluids. It is an immunoassay procedure and is based on an enzymatic colour reaction. It therefore belongs to the enzymatic immunoadsorption methods (EIA).
This test procedure guarantees a very accurate evaluation.
In addition to the nutrition test, this method is used in the veggie and performance test for the protein ferritin.

The kiweno vitamin d quick test can detect the vitamin D level with high reliability.

In cooperation with our parent company Immundignostik AG, a renowned company in the field of laboratory diagnostics, many resources were invested in the development of this innovative rapid test procedure. The new rapid test procedure was of course checked and tested to ensure that the quality of the results was the same as in a laboratory evaluation. A comparative study carried out by Immundiagnostik AG (download) shows that the values measured by the rapid test method are very comparable with the laboratory measurements (measurement with mass spectrometry, ELISA). The kiweno vitamin d rapid test uses the same rapid test procedure as the Preventis SmarTest vitamin D used in the study.

Nevertheless, incorrect results may be obtained in individual cases. If the results are questionable, further clinical tests should be carried out. As with all diagnostic tests, a final finding should not be based on a single result, but only after the clinical picture has been fully clarified by the attending physician.

The vitamin d rapid test has a measuring range of 5-100 ng/ml 25(OH)-Vitamin D.

The test detects 25(OH) vitamin D2, 25(OH) vitamin D3, 1,25(OH)2 vitamin D2 and 1,25(OH)2 vitamin D3. There is no cross-reactivity to 1,24(OH)2-vitamin D2, 1,24(OH)2-vitamin D3 or 3-epi-(OH)-vitamin D3. The kiweno vitamin d rapid test result is not affected by bilirubin, triglycerides, cholesterol, vitamin B12 or vitamin C. The coefficient of variation is 25.8% for repeated measurements with one rapid test batch and 3-37% for repeated measurements with different rapid test batches. A comparative measurement of 27 patient samples with the Schenlltest method and the reference method LC-MS/MS (liquid chromatography-mass spectrometry/mass spectrometry) showed a very good agreement between the two methods (87.5%).

After use, the test with all components can be disposed of in the residual waste.